ANID Exploración 13220082: Looking through the window: A novel complexity-based electroretinogram analysis for neurodegenerative disease diagnosis

Neurodegenerative diseases (NDs) are one of our most significant public health challenges. In these diseases, neurons in specific brain areas progressively and irreversibly deteriorate until they die. Alzheimer’s disease (AD) and Parkinson’s disease (PD) are two of the major NDs and among the leading causes of death in the elderly population.

ANID Fomento a la Vinculación Internacional

Multiscale Entropy Analysis of Retinal Signals Reveals Reduced Complexity in a Mouse Model of Alzheimer's Disease

Alzheimer’s disease (AD) is one of the most significant health challenges of our time, affecting a growing number of the elderly population. In recent years, the retina has received increased attention as a candidate for AD biomarkers since it …

Multi-Scale Entropy Analysis of Retinal Signals in an Animal Model of Alzheimer’s Disease

Quantification of direction selectivity in a network model of the retina

We are studying the phenomenon of direction selectivity to light stimuli in the retina by means of computational models of retinal cell networks.

A DSGC-SAC Network Model of Direction Selectivity in the Mammalian Retina

Model Quantification of Direction Selectivity in Starburst Amacrine Cells in the Mammalian Retina

Detection of motion direction in the visual system of rodents is observed at processing stages as early as the retinal circuitry. Starburst amacrine cells (SAC), which are components of this circuit, appear to give rise to direction selectivity (DS), …

CINV Postdoctoral Fellowship: An integrated biophysical network model of motion direction selectivity in the mammalian retina

Detection of motion and motion direction in the visual mammalian system is observed at processing stages as early as the retinal circuitry (Barlow & Levick 1965). Direction-selective ganglion cells (DSGC) in the retina exhibit higher firing activity in response to visual stimuli moving along a preferred direction, and little to none activity for stimuli moving in the opposite direction (Schachter et al.