Fiber model

Neuroingeniería en la Usach

Medicina Bioeléctrica Computacional

Model Quantification of Axon Responses to Kilohertz SCS for the Treatment of Chronic Pain

Nerve fiber modeling

We are analyzing computational models of nerve fibers to understand how they respond to high-frequency stimulation waveforms. Our goal is to use mathematical modeling and engineering techniques to improve existing models and contribute to the improvement of electrical neuromodulation therapies.

Quantification of dorsal column fiber responses in a model of kilohertz-frequency spinal cord stimulation

Introduction: Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons with chronic pain that is potentially more effective than conventional (~ 50 Hz) SCS. In SCS, the applied electrical …

Quantification of Dorsal Column Fiber Responses in a Model of Kilohertz-Frequency Spinal Cord Stimulation

Introduction Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons with chronic pain that is potentially more effective than conventional (̃50 Hz) SCS. In SCS, the applied electrical …

Effects of frequency-dependent membrane capacitance on neural excitability

Objective. Models of excitable cells consider the membrane specific capacitance as a ubiquitous and constant parameter. However, experimental measurements show that the membrane capacitance declines with increasing frequency, i.e., exhibits …

Mammalian Motor Nerve Fibers, Models of