We are analyzing computational models of nerve fibers to understand how they respond to high-frequency stimulation waveforms. Our goal is to use mathematical modeling and engineering techniques to improve existing models and contribute to the improvement of electrical neuromodulation therapies.
Introduction: Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons with chronic pain that is potentially more effective than conventional (~ 50 Hz) SCS. In SCS, the applied electrical …
Introduction Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons with chronic pain that is potentially more effective than conventional (̃50 Hz) SCS. In SCS, the applied electrical …
Objective. Models of excitable cells consider the membrane specific capacitance as a ubiquitous and constant parameter. However, experimental measurements show that the membrane capacitance declines with increasing frequency, i.e., exhibits …