Transdermal amplitude modulated signal

Nerve excitation using an amplitude-modulated signal with kilohertz-frequency carrier and non-zero offset

BACKGROUND Incorporating kilohertz-frequency signals in transcutaneous electrical stimulation has been proposed as a means to overcome the impedance of the skin, thereby reaching deeper nerves. In particular, a transdermal amplitude modulated signal …

Volume conductor model of transcutaneous electrical stimulation with kilohertz signals.

OBJECTIVE: Incorporating high-frequency components in transcutaneous electrical stimulation (TES) waveforms may make it possible to stimulate deeper nerve fibers since the impedance of tissue declines with increasing frequency. However, the …